刚下了avastin官网的用药指南:
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Patients should continue treatment until disease progression or unacceptable toxicity. 6 D" f4 d4 P* T' d7 O' @! \
1 Metastatic Colorectal Cancer (mCRC)
$ L# C. N4 ^$ a! X+ y% T The recommended doses are 5 mg/kg or 10 mg/kg every 2 weeks when used in combination with 2 l/ `, G+ s! k: G0 l
intravenous 5-FU-based chemotherapy. / |- W0 A- O' y, R8 |
• Administer 5 mg/kg when used in combination with bolus-IFL. - \! w2 E9 N' I# y5 o
• Administer 10 mg/kg when used in combination with FOLFOX4.
4 q p" ]! k" ^* D% O2 Non-Squamous Non-Small Cell Lung Cancer (NSCLC) ( s: L$ f" c! r
The recommended dose is 15 mg/kg every 3 weeks in combination with carboplatin and d2 L. A v4 ~! ~
paclitaxel. ( G- K+ f0 ]4 G3 m& J* z! I
3 Metastatic Breast Cancer (MBC)
' e2 n. s" o' X7 E" ^# X6 v The recommended dose is 10 mg/kg every 2 weeks in combination with paclitaxel.
' _1 ]( j% @/ |+ `6 _- {( w! K4 Glioblastoma
1 o6 ~/ o# m+ a, s( O `- j The recommended dose is 10 mg/kg every 2 weeks.
, n: g! u. }( R3 Q5 Metastatic Renal Cell Carcinoma (mRCC)
! ]9 w+ J# m( r( p. ] The recommended dose is 10 mg/kg every 2 weeks in combination with interferon alfa. ; X. N4 f# {" |7 }' R
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按照这个说明非小细胞腺癌的服用剂量是15mg/kg,与卡铂紫杉醇合用,avastin每三周用一次。
: L$ M0 A: Y& |; P6 _我妈妈是肺腺癌转肝,体重53kg,现在医生联合卡铂紫杉醇化疗了一个疗程21天。 但avastin不是一次注射的,每7天注射一次200mg,一个疗程21天注射了3次(分别是第一、八、十五天) |