靶向药期间是否有进展？
去年六月份确诊肺腺癌VIBc T4N2MIc，因为没有手术机会，经基因检测后检查出ALK突变，期间三个月复查一次，肿瘤一直有缩小，一线治疗从去年六月底服用布格替尼至今，最近一周出现刺激性干咳，偶尔痰中带血，食欲减退，且有憋气感觉，怀疑颈部双侧淋巴结肿大，请问这种情况是否意味着靶向药已经耐药，目前准备周一去检查，请大家帮忙给一个给意见，这种情况是否代表已经进展，如果要复查可以针对性的检查一些其他项目吗，10月份复查的胸部CT，B超，核磁MR结果都是稳定的。以下附出院报告，基因检测报告，最近一次复查的胸部CT报告，核磁MR报告，癌胚抗原报告。https://oss.yuaigongwu.com/pic/20241116/1731731466248561592.jpg
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颈部淋巴结做个彩超就可以判断出有无问题吧？
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